The question should be dose your motherboard support dual pci-e x16??
the cpu it self would have no problem with it.
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PII 1100T (Extinct) Asus M4A78T-E (should be Extinct) 4Gb of Corsair XMS3 1600Mhz DDR3 (Going strong) 2x1GB 5850's (On their last lags) Corsair HX850W (Awsome) NZXT Phantom case (too ***** big)