I am seeing this same problem in a business enviroment, so no gaming going on.
We use PE builds of Windows and recently were attributing the problems to that particular build. We just discovered that it is not isolated to that version of Windows. Below are several of our test cases and specs to follow. Any ideas are appreciated.
Test 1 - PE build with latest drivers will run for approx 24hr before mouse distorition occurs, enabling mouse trails makes pointer look correct, however with or without mouse trails, when doing any form of reboot/shutdown, the computer only goes down partially and a hard power is required to take it all the way down.
Test 2 - PE build with latest drivers from HP (older than AMD release), same symptoms above
Test 3- Non pe build, same symptoms as above, however, time before failure is >5 days. With this version we currently have 10 identical machines running with differents levels of our internal software, including no internal or 3rd party software, to full 3rd party/internal software.
The problem is that all "solutions" or others with same issues are occuring on gaming systems and most can be fixed with a little mouse jiggle, whereas our machines are idle with no user interaction and only resolve with a reboot or unistalling video drivers within windows. Once video drivers are uninstalled, pointer returns to normal, reinstall drivers, pointer is normal.
In all of the scenarios windows does not detect a "problem" and aside from being unhappy that we did a hard power, it is oblivious to the problem.
HP6305 SFF and MT
AMD/ATI Radeon HD 7480D
AMD A4-5300B APU 3.4GHZ
Split between all testing units, PS2-KVM, USB KVM, straight PS2 no switch