I am having a lot of problems that seem to stem from my AMD GPU.
I am running the retail version of Doom 3 with the 1.3.1 patch. The screen resolution won't save.
I also can't run any mods.
After reading complaints of the same problem they all seem to point to having an AMD GPU and CatalystAI.
My System:
CM Storm Scout, AMD Phenom II X4 965 Deneb Black Edition @ 3.4Ghz w/Cooler Master Hyper212, MSI 870-G45, Corsair XMS3 4gb (2x2gb) 240-Pin DDR3 SDRAM DDR3 1600 @ 1600 Mhz, Sapphire Radeon 6870, WD Caviar 500gb, Sony Combo CD/DVD, Corsair Modular HX620