I can´t simply install any new drivers for my Radeon HD 5850. The drivers who works is the one i got with the card on a CD. When i try to install any new drivers an restart my computer I get a message that i don´t have any drivers. 

Info: 

PowerColor Radeon HD 5850  PCI-E 

Diver version: 8.663.0.0

Operating System: Windows 7 64-bit

Motherboard: Gigabyte P55A-UD4

Power Supply: Corsair 550 W

Display Device: Benq G2412HD HDMI

Samsung SyncMaster 920n DVI

CPU: Intel(R) Core(TM) i5 CPU 750 @ 2.67 GHz

Please read the sticky thread and provide the requested information.

CPU: AMD Phenom II X4 810 @ 3250MHz | RAM: Kingmax 2x2GB DDR2 800 @ 833MHz| MoBo: MSI K9A2 CF v1.0 (BIOS: 1.D)| GPU: Asus HD 6850 1024MB (DirectCu) @ 850/1100MHz | Display: Chili Green Vision L24FHD | PSU: PC Power & Cooling Silencer 750 Quad | OS: MS Windows 95 x64 Edition

CPU: Pentium 4 Northwood S478 @ 3200MHz | RAM: 1,5GB DDR 400| MoBo: Gigabyte GA-8S661FXMP-RZ | GPU: Abit Geforce Ti 4200 | Display: Dimarson 19" CRT | PSU: Noname 400W | OS: MS Windows XP Pro, Fedora 18

This may or may not work. Good place to start  though.

Install the ones from the CD.

Download and run the installer for the latest catalyst suite.

DO NOT uninstall anything, just let it install overtop the existing drivers.

#1: Phenom II C2 955BE @ 3.6, Antec Kuhler 920, Gigabyte GA-MA790FX-DS5, Asus 5870/V2, ASUS Xonar D2X, 4 x 1gig OCZ2N1066SR2GK @800, Antec Truepower New 750, Arc Midi, Win8pro x64 upgrade
#2: Athlon 64 X2 4200+, AGP 1950pro, Audigy 2, Asus A8V-D, 2gig ram,  Enermax 465P, Antec900. Now on Win8pro cat 10.2

You mean a message box appears with the text "you don't have any drivers"? It's hard to imagine. I can assure you its source is not the Catalyst Install Manager. It may be malware, someone f****ing with you, or you didn't describe the issue properly.

CPU: AMD Phenom II X4 810 @ 3250MHz | RAM: Kingmax 2x2GB DDR2 800 @ 833MHz| MoBo: MSI K9A2 CF v1.0 (BIOS: 1.D)| GPU: Asus HD 6850 1024MB (DirectCu) @ 850/1100MHz | Display: Chili Green Vision L24FHD | PSU: PC Power & Cooling Silencer 750 Quad | OS: MS Windows 95 x64 Edition

CPU: Pentium 4 Northwood S478 @ 3200MHz | RAM: 1,5GB DDR 400| MoBo: Gigabyte GA-8S661FXMP-RZ | GPU: Abit Geforce Ti 4200 | Display: Dimarson 19" CRT | PSU: Noname 400W | OS: MS Windows XP Pro, Fedora 18

Hmmm....I haven't updated the driver for my 5850's in a while but...I've been uisng the 12.6 drivers for a while now.

I'll update it to the newer ones and see if anything weird happens.

Phenom II X6 1090T @ 4.1GHz // ASUS Crosshair V Formula 990FX // Sapphire Radeon HD Dual-X 7970 // Thermaltake Frio w/ push-pull (using Antec Formula 7 Nano Diamond paste!!) // 8GB (2 X 4GB) G.Skill RipJaws DDR3 1600MHz @ 8-9-8-34-21-1T // Corsair TX850 850W // Corsair Force GT 120GB SSD (OS) // Kingston 200 V+ 120GB SSD // WD Caviar Black 1TB // Windows 7 Ult x64 // Logitech X-540

unfortunately it did not work, still got the same problem but thx for trying ! 

The message says "No ATI-graphicdrivers is installed or not working properly. Install the correct ATI-drivers for your ATI-hardware"

I have tried alot of different drivers  

It won't hurt to run the .net 3.5 installer just to make sure you have all the components.

#1: Phenom II C2 955BE @ 3.6, Antec Kuhler 920, Gigabyte GA-MA790FX-DS5, Asus 5870/V2, ASUS Xonar D2X, 4 x 1gig OCZ2N1066SR2GK @800, Antec Truepower New 750, Arc Midi, Win8pro x64 upgrade
#2: Athlon 64 X2 4200+, AGP 1950pro, Audigy 2, Asus A8V-D, 2gig ram,  Enermax 465P, Antec900. Now on Win8pro cat 10.2

Maybe windows update overwriting your drivers, so you have a driver-CCC mismatch.

CPU: AMD Phenom II X4 810 @ 3250MHz | RAM: Kingmax 2x2GB DDR2 800 @ 833MHz| MoBo: MSI K9A2 CF v1.0 (BIOS: 1.D)| GPU: Asus HD 6850 1024MB (DirectCu) @ 850/1100MHz | Display: Chili Green Vision L24FHD | PSU: PC Power & Cooling Silencer 750 Quad | OS: MS Windows 95 x64 Edition

CPU: Pentium 4 Northwood S478 @ 3200MHz | RAM: 1,5GB DDR 400| MoBo: Gigabyte GA-8S661FXMP-RZ | GPU: Abit Geforce Ti 4200 | Display: Dimarson 19" CRT | PSU: Noname 400W | OS: MS Windows XP Pro, Fedora 18

Hmm.. how exactly does it work, never used it before ? 

I have tried to get a newer version of the drivers threw windows update and getting it from amd website  

Just run the installer and let it do it's thing. It's a no brainer.

#1: Phenom II C2 955BE @ 3.6, Antec Kuhler 920, Gigabyte GA-MA790FX-DS5, Asus 5870/V2, ASUS Xonar D2X, 4 x 1gig OCZ2N1066SR2GK @800, Antec Truepower New 750, Arc Midi, Win8pro x64 upgrade
#2: Athlon 64 X2 4200+, AGP 1950pro, Audigy 2, Asus A8V-D, 2gig ram,  Enermax 465P, Antec900. Now on Win8pro cat 10.2

Installed .NET Framework 4.5. 

And tried to install drivers 10.10e version last night, still same problem  

I solved the problem  

Installed windows from scratch and took the drivers from the webbsite instead of the CD, and that work